Clinical Observation of Choroidal Osteoma Using Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography

Choroidal neovascularization (CNV) secondary to choroidal osteoma (CO) can cause profound visual loss, but detecting CNV and the tumor’s feeder vessels using traditional fluorescent angiography imaging is challenging. Newly developed TowardPi swept-source optical coherence tomography (SS-OCT) OCT (SS-OCTA) enable ultra-high resolution, enhanced penetration with longer wavelength (1060 nm), a rapid scan rate (400 KHz), reduced loss of signal strength increasing depth, 120° angular widefield fundus view, enabling nearly histological description retina choroid. We therefore used this SS-OCT SS-OCTA platform observe intrinsic features in 23 eyes 21 patients. It was found that borders CO were clearly demarcated from adjacent Sattler’s Haller’s layers, while on corresponding B-scan blood flow detected mainly within choriocapillaries partly layer. The identified as numerous branching or radiating connecting displaying various patterns including ginseng, instant noodle, growth ring, tangle, spider web, medusa, seafan, irregular shape. Moreover, tumor-like tissues grow above disrupted Bruch’s membrane. be detect tumor vasculature CO.